Yaws and other endemic treponematoses

report of a Regional Meeting, Brazzaville, 3-6 February, 1986.

Publisher: World Health Organization, Regional Office for Africa in Brazzaville

Written in English
Published: Pages: 73 Downloads: 313
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Subjects:

  • Treponematoses -- Congresses,
  • Yaws -- Congresses

Edition Notes

We review the dilemmas in the diagnosis of endemic treponematoses, and advances in the discovery of new diagnostic tools. - References for this review were identified through searches of PubMed and WHO databases from January 1, to January 1, , by use of terms yaws, pian, bejel, pinta, carate, endemic Treponematoses, and Treponema pallidum.   Yaws is a common infectious disease among children living in the tropical areas of Africa, South and Central America, the West Indies, and the Far East. It is not known in the United States. Yaws affects males and females in equal numbers and is most . Herman Jan H. Engeikens, M.D., Paul L. A. Niemei, M.D., Jaap J. van der Siuis, Ph.D. Andre Meheus, M.D., and Ernst Stoiz, M.D. Treponemal infections occurring in humans comprise venereal syphilis and the endemic treponematoses yaws, pinta, and endemic syphilis. The endemic treponematoses have comparable natural histories. Young children are at the highest risk to acquire the nonvenereal. Yaws is a nonvenereal endemic treponemal infection caused by T. pallidum subspecies pertenue. Yaws is a chronic relapsing disease spread through skin-to-skin contact and causing skeletal and mucosal lesions that can become destructive (Marks et al., ). Skeletal involvement is estimated to be between 5% and 15% (Steinbock, ).

Yaws and the other endemic treponematoses (bejel or endemic syphilis, pinta) are resurging in many countries of Africa. Today there are more than million cases of these diseases, 75% of them. These matters are not yet fully understood and International Journal of Dermatology â ¢ February Vol. 30 Figure 1, Geographical distribution ofthe endemic treponematoses in the early s, Reprodueed with permission from Perine PL, et al. Handbook of Endemic Treponematoses: Yaws, Endemic Syphilis, and Pinta, Geneva: World Health. It is now generally agreed that the treponematoses constitute a closely related group of infections which in different environments develop different but similar syndromes (Treponema pallidum, pertenue and carateum). It is estimated that there are 40 million cases of yaws and several million of endemic syphilis in the world; those most affected are young people, especially children, and rural.   By the end of the s a resurgence of the endemic treponematoses had occurred in many areas of the world. The necessity for renewed efforts was recognized by the World Health Assembly and expressed in WHA Resolution YAWS ERADICATION PROGRAMME Introduction Yaws is a disfiguring and debilitating non-venereal disease.

Endemic syphilis: Lesions are histopathologically identical to those of venereal syphilis. TREATMENT OF ENDEMIC TREPONEMATOSES The recommended treatment for pinta, yaws, and endemic syphilis is a single injection of million units of benzathine penicillin in adults or children over 10 years of age and million units in younger children. Yaws is a tropical infection of the skin, bones and joints caused by the spirochete bacterium Treponema pallidum pertenue. The disease begins with a round, hard swelling of the skin, 2 to 5 centimeters in diameter. The center may break open and form an ulcer. This initial skin lesion typically heals after three to six months. After weeks to years, joints and bones may become painful, fatigue.   Treponema pallidum subsp. endemicum is the causative agent of endemic syphilis, also called nonvenereal syphilis. Other diseases caused by nonvenereal treponematoses are yaws (T. pallidum subsp. pertenue) and pinta (T. carateum).

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Handbook of endemic treponematoses: Yaws, endemic syphilis, and pinta Paperback – January 1, by World Health Organization (Author) See all formats and editions Hide other formats and editionsAuthor: World Health Organization.

The treponemal infections that occur in humans are venereal syphilis and the endemic treponematoses (yaws, endemic syphilis and pinta). The endemic treponematoses, all of which are chronic relapsing tropical diseases, have similar natural histories. Young children are at the highest risk of acquiring these nonvenereal : Herman Jan H.

Engelkens. endemic treponematoses yaws, bejel (or endemic syphilis), and pinta, respectively. All human treponematoses share remarkable lung, liver, brain, other organs) Vertical transmission Not commonly recognized but asserted (43) Not commonly recognized but asserted () Not recognized Frequent Central nervous system involvementCited by:   Abstract.

Previous mass campaigns against the endemic treponematoses have taught investigators several lessons that, along with current constraints and altered circumstances, must be considered in the formulation of a contemporary strategy for the control or eradication of yaws, endemic syphilis, or by: The results confirm that yaws is underreported and that it persists and is even resurgent in many areas of Togo and in other French-speaking countries in West Africa.

Because of the prevalence of migration and nomadism, a regional (as opposed to national) effort to combat the treponematoses is essential.

Introduction. Treponematoses are infections caused by the spirochetal organisms of the Treponema species. These bacteria are the cause of both syphilis (Treponema pallidum ssp.

pallidum) and the so-called nonvenereal or endemic treponematoses (ETs) consisting of yaws (T. pallidum spp.

pertenue), bejel (or endemic syphilis) (T. pallidum spp. endemicum), and pinta (T. carateum). World Health Organization () International Symposium on Yaws and Other Endemic Treponematoses. Washington DC, April 16–18, Rev Infect Dis 7: – View Article Google Scholar Gazin P, Meynard D () A clinical and serologic survey of bejel in north Burkina Faso.

Yaws (also known as framboesia or pian) is a chronic disease of childhood caused by spiral bacteria Treponema pallidum subspecies pertenue and part of the larger group of endemic treponematoses.

The disease affects the skin, bones and cartilage and causes disfigurement and debilitation. The global prevalence of this disease and the other endemic treponematoses, bejel and pinta, was reduced by the Global Control of Treponematoses (TCP) programme between and from about 50 to million cases to about million (a 95 percent reduction).

Following the cessation of this program yaws surveillance and treatment became a. Akademie der Wissenschaften Book ) - Kindle edition by Hacket, C.J.

Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Diagnostic Criteria of Syphilis, Yaws and Treponarid (Treponematoses) and of Some Other Diseases in Dry Bones: For Use in Manufacturer: Springer.

Perine PL, Hopkins DR, Niemel PLA, St John RK, Causse G, Antal GM Handbook of endemic treponematoses: yaws, endemic syphilis, and pinta. World Health Organization, Geneva, Google Scholar. De Schryver A, Meheus A Endemic treponematoses: an old health problem which appears again.

Medécine Tropicale– Yaws presents with an initial primary lesion (papilloma) that is often ulcerative. Endemic treponematoses. In: Letters submitted for publication in AFP must not be submitted to any other.

Title: Yaws and Other Endemic Treponematoses 1 Yaws and Other Endemic Treponematoses. Jack McCarrick; 2 Yaws and its relatives are caused by spirochete bacteria Treponema pallidum 3 The endemic treponematoses are mainly transmitted by human-to-human contact 4 Yaws is typically found in tropical areas of Africa, South America, and Asia 5.

Bejel, pinta, and yaws (endemic treponematoses) are chronic, tropical, nonvenereal spirochetal infections spread by body contact. Symptoms of bejel are mucous membrane and cutaneous lesions, followed by bone and skin gummas.

Yaws causes periostitis and dermal lesions. Pinta lesions are confined to the dermis. Endemic treponemal diseases are non-venereal infections closely related to syphilis.

They consist of yaws, bejel (endemic syphilis), and pinta. They are endemic in tropical rural areas and very rare in Europe. Increasing worldwide migration from endemic areas requires recognition of these diseases by physicians in developed countries.

Generally, yaws flourishes in moist tropical areas of several regions, endemic syphilis is found primarily in arid climates, and pinta is found in temperate foci in the Americas (Fig.

e-1). These infections are usually limited to rural areas of developing nations and are seen in developed countries only among recent immigrants from endemic. The endemic treponematoses are chronic, granulomatous diseases caused by morphologically and serologically identical spirochaetes of the genus Treponema.

They are spread by intimate but non-sexual contact and possibly by fomites, mainly among children. Treponema pallidum subsp. pertenue causing yaws (framboesia), T. pallidum subsp.

endemicum causing endemic syphilis (bejel) and T. carateum. Summary report of a conSultation on eradication of yawS which yaws and other endemic treponematoses occur.

He stressed that, in an eradication programme, every effort and every approach should be used to identify, treat and report each case systematically. Dr Kingsley Asiedu, head of the yaws eradication programme in the Department of Control of.

Handbook of Endemic Treponematoses: Yaws, Endemic Syphilis, and Pinta. WHO Publications Centre, USA: World Health Organization; Second International Conference on Control of Yaws.

Report of Second International Conference on Control of Yaws: Nigeria, II. J Trop Med Hyg. Mar. 60(3)   The endemic treponematoses include yaws (Treponema pallidum subsp pertenue), bejel (T. pallidum subsp endemicum), and pinta (Treponema carateum) [ 1 ]. – Endemic treponematoses are bacterial infections caused by 3 different types of treponema (other than Treponema pallidum).

Human-to-human transmission may be direct or indirect. – The 3 endemic treponematoses result in positive syphilis serology (TPHA-VDRL), but these tests are not necessary as diagnosis is clinical. There is no laboratory. Note: Citations are based on reference standards. However, formatting rules can vary widely between applications and fields of interest or study.

The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be applied. INTRODUCTION Treponemal infections of humans have a worldwide distribution and include both venereal syphilis, caused by Treponema pallidum subsp.

pallidum and the endemic treponematoses, which include yaws (T. pallidum subsp. pertenue), pinta (Treponema carateum), and endemic syphilis (T.

pallidum subsp. endemicum). World Health Organization () International Symposium on Yaws and Other Endemic Treponematoses. Washington DC, April 16–18, Rev Infect Dis 7: – [Google Scholar] Gazin P, Meynard D () A clinical and serologic survey of bejel in north Burkina Faso.

Bull Soc. Treponematosis, also known as treponemiasis, traditionally refers to the group of nonvenereal diseases (including endemic syphilis [nonvenereal syphilis]) caused by Treponema species that are morphologically and serologically identical to each other and to Treponema pallidum subspecies pallidum, the cause of venereal syphilis.

They differ onl. Yaws is a bacterial infection of the skin and bones (Figure 1), caused by the spirochete Treponema pallidumsubspecies pertenueand transmitted by contact.

The yaws treponemes are very closely related (differ in less than % of the genome sequence) to syphilis treponemes (T. pallidumsubspecies pallidum), although they are less virulent. Chronic bacterial infections from treponemes can include syphilis, which is sexually transmitted, and endemic treponematoses.

Among frambesia, bejel, and pinta, the three types of endemic treponematoses, frambesia is the most common. Yaws is transmitted via fluid from the lesion of an infected person through direct interpersonal nonsexual contact.

regional meeting on yaws and other endemic treponematoses. Cipanas, Indonesia, July 22–24, Southeast Asian J Trop Med Public Health 17(4 Suppl): 1– WHO () Regional Meeting on yaws and other endemic treponematoses. 3– 6 FebruaryBrazzaville, Congo (AFR/CD/58).

Geneva: World Health Organization. The endemic, or nonvenereal, treponematoses are infections caused by bacteria that are closely related to Treponema pallidum pallidum, the etiologic agent of venereal include Treponema carateum (pinta), Treponema pallidum pertenue (yaws), and Treponema pallidum endemicum (bejel or endemic syphilis).

The diseases are distinguished from venereal syphilis by. This challenging but potentially feasible endeavor is favored by the adoption of oral azithromycin for mass treatment and the currently focused distribution of yaws and endemic treponematoses and.

The history of yaws eradication efforts illustrates the importance of political support. Yaws ticks all the required features for disease eradication: it is caused by only one species of bacteria, only infects humans and non-human primates, good and cheap means against and diagnostics for yaws exist and both some countries have successfully interrupted its transmission.ISBN: OCLC Number: Description: 59 pages, 39 unnumbered pages of plates: color illustrations ; 24 cm: Responsibility.Yaws, pinta, and endemic syphilis (bejel) are all grouped together as nonvenereal endemic treponematoses, which are chronic bacterial infections caused by treponemes.

These are mostly prevalent among communities living in poor, unhygienic conditions in hot and humid areas.